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Product Size: 60 tablets
Serving Size: 1 tablet
Servings per Container: 60
Manufacturer: Jarrow Formulas
Item Number: JRF-001-060

Promotes

• Joint Strength*
• Liver Detoxification*
• Mood and Brain Function*

Jarrow Formulas SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

Suggested Use

Take one tablet per day on an empty stomach, or as directed by your qualified healthcare professional.

Supplement Facts:

Serving size: 1 tablet
Servings per container: 60

Amount per serving:

• S-Adenosyl Methionine (from 800 mg of SAM-e tosylate disulfate) — 400 mg

Other Ingredients: Cellulose, glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, mannitol, sodium starch glycolate, and an enteric coating (methacrylate copolymers, magnesium silicate, titanium dioxide, triethyl citrate, silicon dioxide and riboflavin).

Suitable for vegetarains/vegans. No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.

Warning

Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using this product. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e. Do not use if pregnant or nursing. Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use. Store in a cool, dry place. Keep out of reach of children.

Dietary Considerations

• Wheat Free
• Dairy/ Milk Free
• Gluten Free
• Vegetarian
• Soy Free
• Vegan
• Egg Free
• Shellfish Free

More About SAM-e 400

SAM-e has been clinically shown to have the following benefits:

• Joint Strength: SAM-e supports the production of healthy connective tissue through transulfuration.* In this process, critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAM-e metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.*
• Brain Metabolism: SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).*
• Liver: SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-stransferase), which are substances important for liver function, including phase 2 detoxification.*

Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active from is the (S,S) structure while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAM-e the highest active level available.