Your Holistic Doc Specialty Labs

 

At Your Holistic Doc, we know that not all labs are the same. For this reason, Dr. Cometa has used Specialty Laboratories when necessary to get her patients the best evaluation for treatment available. The laboratories and their tests used by Dr. Cometa are very carefully selected for their efficacy and reliability and have been in her practice for over 20 years.

Dr. Cometa is now offering one time virtual consultations through ZOOM for an additional fee. Whether you are in Oregon or around the corner from Your Holistic Doc, LLC, you can schedule a Wellness Labs consultation to review your labs. Click here to schedule consultation with Dr. Cometa.  

What You Get

Test results are sent directly to you from Cometa Wellness Center. These will include Dr. Cometa’s preliminary feedback suggesting whether or not you should consider scheduling a follow-up consulting appointment with Dr. Cometa to get a full interpretation of the results.

What is Intestinal Permeability?

Intestinal Permeability (i.e. “Leaky Gut”) is a condition where the integrity of the intestinal cell barrier is compromised/broken down. Normally, our intestinal cell network forms a very important barrier between our digestive tract (outside environment) and our blood stream (inside environment). With Intestinal Permeability, the barrier is broken down and intestinal contents can enter the blood stream.

When the intestinal lining is compromised and it is considered Permeable or “Leaky”, it is the tight junctions of our intestinal epithelial cells (bowel lining) that have been broken down. When this occurs and the main barrier between our digestive tract and our blood stream has been damaged, we can have a variety of symptoms. 

A short list of some of the more common Symptoms of Leaky Gut:


  • Gas
  • Bloating
  • Fatigue
  • Abdominal pain
  • Diarrhea
  • Constipation
  • Headaches
  • Brain fog
  • Rashes, such as eczema
  • Nausea and vomiting
  • Skin itchiness and redness
  • Bronchitis and asthma-like symptoms
  • Musculoskeletal joint pain
  • Muscle stiffness and swelling


Why do we get Intestinal Permeability or Leaky Gut?  Critical to understanding Leaky Gut is to realize that there are many factors involved, from the:

1) breakdown of immune regulation managed by the intestinal lining

2) loss of immune tolerance with resulting hypersensitivity and immune mediated reactivity to foods we eat

3) degradation/breakdown of the intestinal mucosa (bowel lining)

4) loss of gut microbial diversity (bacteria in the gut become imbalanced) with associated Dysbiosis (i.e.  imbalanced bacteria in the gut)

 

FOOD SENSITIVITY TESTING vs. FOOD ZOOMERS TESTING

Food sensitivity testing detects reactivity to whole protein-based antigens found in foods, while Food Zoomer testing measures peptide-level sensitivities. In other words, Food Sensitivity only tests sensitivity to undigested food proteins and Food Zoomers tests sensitivity to the whole proteins but is also to test every peptide within the protein (thousands of possible reactions). Why is this difference between the two types of Food Reaction testing so critically important?

Protein moieties are found in all food. These proteins are broken down into smaller constituents called Peptides through digestion, so they can be absorbed as amino acids back into the blood stream.

It is at this point in the process of digestion with the unfolding of the protein moieties into the breakdown peptides that the immune system which resides within our gut can react to these “foreign” proteins. Once considered foreign, antibodies to these breakdown Peptides can cause intestinal mucosa barrier permeability and result in Leaky Gut.

Rarely will a person’s immune system be exposed only to the whole protein form of foods because once food reaches the small intestine it has been broken down in the stomach by hydrochloric acid and enzymes. Yet, information about antibodies formed in the body to the whole protein gleamed from Food Sensitivity testing  (aka Food Allergy testing) , are often helpful because they can be an indicator that a patient lacks sufficient digestive capacity (HCl and enzymes) when these whole protein sensitivities detecting whole protein antibody immune reaction in the person.

Antibodies to whole proteins will not bind to peptides, and vice versa. SO, why limit food sensitivity testing to the whole protein antibody testing?

FOOD ZOOMERS measure the whole protein reactivity AS WELL AS the proteins breakdown products, called polypeptides and peptides.  When measured, the reactivity to the food protein breakdown peptides proves to provide the most accurate measurement of the body’s reactivity to a food under realistic conditions when the proteins are broken down into peptides in the GI Tract.

The Vibrant Food Zoomers provide the most in depth and accurate look at true food sensitivities because they can measure thousands of peptides in one whole protein for a full spectrum of reactivity. This highly accurate and reproducible testing looks at the immune responses to peptides within these antigenic ( aka allergic) foods as compared to all other food sensitivity tests which measure antibodies to whole proteins, which is not a complete assessment because  they are  not actually not what our immune system is exposed to in real life during digestion.

But remember, that in reality, patients with digestive problems and inflammatory conditions/symptoms commonly have hypochlorhydria and deficiencies of enzymes and/or bile acids, so whole protein testing has its place, because they are often an indicator that a patient lacks sufficient digestive capacity (HCl and enzymes) when these whole protein sensitivities are detected.

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  • Vibrant uses mass spectrometry technology to measure levels of mycotoxins in urine, and is able to detect molecules as small as 5 pcg, which greatly expands the number of detectable mycotoxins. 
  • It is important to point out the Differences here between mold Spores and mold Mycotoxins. Sick Building Syndrome is often ruled out in a symptomatic patient because the testing is limited to Mold Spore testing, which is often not the issue for these patients.
    Mold Illness due to Mold Spores causes a limited spectrum of symptoms due to the fact that mold spores cause a different reaction in the body called a Type 1 Hypersensitivity reaction. These symptoms often involve the respiratory tract and include but are not limited to:
    • allergy symptoms
    • rhinitis asthma
    • hypersensitivity pneumonitis

    Mold Mycotoxins are poorly understood and are tiny tiny lipophilic nanoparticles which the body rapidly absorbs. Interestingly, these Mycotoxins are what cause the smell of mold (or mildew).

    Because Mold Spores are what are often tested in patients, the highly mold reactive person is often not correctly tested when the testing is limited Mold Spore testing.

    Mold Mycotoxins testing with Vibrant Mycotoxin urine screening offers an entirely new avenue to evaluate a person for Mold Toxicity:

    Conditions and symptoms associated with mycotoxin exposure include but are not limited to:

    • Fatigue and weakness 
    • Chronic burning in the throat and nasal passages
    • Coughing, wheezing, and shortness of breath
    • Chronic Sinus issues
    • Loss of balance and DIzziness
    • Depression and/or anxiety
    • Skin rashes
    • Eye irritation or tearing of the eyes
    • Headache and/or light sensitivity
    • Hearing loss
    • Heightened sensitivity to chemicals and foods
    • Irregular heartbeat
    • Morning stiffness and/or joint pain
    • Muscle weakness
    • Sleep problems
    • Poor memory, difficulty finding words  and slower reaction time
    • Vision changes
    • Difficulty concentrating
    • Abdominal pain, diarrhea, and/or bloating
    • Unusual skin sensations, tingling, and numbness
    • Metallic taste in the mouth
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    CDSA 2.0 Brochure (PDF)

    Patient Instructions (PDF)

    What You Get

    Test results are sent directly to you from Cometa Wellness Center. These will include Dr. Cometa’s preliminary feedback suggesting whether or not you should consider scheduling a follow-up consulting appointment with Dr. Cometa to get a full interpretation of the results.

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    Sale

    The Comprehensive Melatonin Profile is a convenient, non-invasive salivary hormone test that analyzes the circadian secretion patterns of melatonin. Using a complete light-dark cycle, this hormone test reveals abnormal levels of melatonin that relates to various physical and psychological symptoms as well as premature acceleration of the body's aging process.

    Melatonin Hormone Testing

    Genova Diagnostics' Comprehensive Melatonin Profile offers many distinct clinical advantages. This hormone test:

    • Analyzes three saliva specimens taken at morning, noon, and midnight. This type of hormone testing allows for evaluation of melatonin activity of a complete light-dark cycle
    • Measures salivary levels which correlate well with serum testing. This hormone test offers a safe, economical, and non-invasive way of assessing pineal function and melatonin secretion patterns

    Once hormonal imbalances have been identified, results can be used to design and implement successful therapeutic programs, including timed application of bright light, removal of interfering factors, and melatonin administration.

    Melatonin imbalances have been associated with a wide array of health problems, including:

    • Sleep disorders
    • Depression
    • Seasonal Affective Disorder (SAD)
    • Chronic progressive multiple sclerosis
    • Menstrual irregularities

    Melatonin's synthesis and secretion can be strongly influenced by day length, artificial illumination, electromagnetic energy, exercise, seasonal changes, impairment in methionine metabolism, and aging. Since synthesis and secretion are easily disrupted, accurate assessment of levels and circadian rhythm is critical.

    The Role of Melatonin

    Melatonin is synthesized within the pineal gland from tryptophan during the dark phase of the day. With its unique ability to pass through all blood barriers in the body, melatonin acts as the central hub of physiological function. Melatonin's role is to:

     

    • Orchestrate the complex interactions between the mind, body, and environment
    • Influence most of the autonomic, hormonal, and behavioral functions of the human organism
    • Advance sleep time and duration
    • Modulate annual and circadian biorhythms (thereby reducing symptoms of jet-lag)
    • Regulate the body temperature
    • Regulate cardiovascular function
    • Regulate immune function, with a possible role in fighting cancer
    • Act as an antioxidant
    • Regulate female reproductive hormones

    Test Type: Saliva Test

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