Glucose Control Pro

A growing body of evidence suggests that specific, naturally occurring gut bacteria, particularly Akkermansia muciniphila and butyrate-producing microbes, are under-represented in the intestinal tracts of individuals with type 2 diabetes. The functions of these microbes, specifically maintenance of gut barrier integrity and butyrate production, are important to glucose and insulin homeostasis¹. The short-chain fatty acid, butyrate, is shown to be essential in glucose management by binding to receptors in the gut mucosa and stimulating the release of glucagon-like peptide-1 (GLP-1). GLP-1 is reduced in individuals with impaired glucose tolerance, which contributes to hyperglycemia. The benefits of GLP-1 impact health beyond diabetes management. In addition to supporting improved glucose control, GLP-1 promotes satiety, boosts general metabolic health, and supports improved cardiovascular health. In a placebo-controlled clinical trial, subjects administered a proprietary blend of Clostridium butyricum, Anaerobutyricum hallii, Clostridium beijerinckii, Akkermansia muciniphila, and Bifidobacterium infantis had significant improvements in glucose total area under the curve (AUC) and reductions glycated hemoglobin (A1C)¹. This five-strain formulation is available as Glucose Control.

To promote the benefits of healthy blood sugar, soluble fiber is imperative as a major energy source for gut microbes and substrate for butyrate production. To optimize the presence of Akkermansia muciniphila, polyphenol-rich prebiotic foods are not only beneficial antioxidants, but have also been shown to increase Akkermansia population in the gut².