Methylation and Neurochemistry

Methylation status testing with Histamine Whole blood:

• Whole Blood histamine levels are used as a marker for methylation status. Histamine, in its whole blood form, is utilized as an accurate marker for under methylation or over methylation.
• Elevated whole blood histamine levels indicate under-methylation. Review of symptoms and medical history can bolster the diagnosis. For example, most under-methylated persons exhibit seasonal allergies, perfectionism, strong wills, slenderness, OCD tendencies, high libido, depression.
• Low whole blood histamine levels indicate over-methylation. Persons who are over-methylated generally exhibit high anxiety, panic disorders, absence of seasonal allergies, presence of food/chemical sensitivities, dry eyes, low perspiration, artistic/music interests/abilities, intolerance to Prozac and other SSRI’s, etc.
• Conditions associated with under-methylation are: Anorexia, Bulimia, shopping/gambling disorders, depression, schizo-affective disorder, delusions, oppositional-defiant disorder, OCD.
• Conditions associated with over-methylation are: Anxiety/Panic disorders, anxious depression, hyperactivity, learning disabilities, low motivation, paranoid schizophrenia, hallucinations. (Oct 3, 2003) Most persons with depression, oppositional defiant disorder, OCD, bipolar disorder, or schizophrenia exhibit a genetic abnormality in methylation which appears to be central to their illness. Carl Pfeiffer, MD, PhD of Princeton, NJ was a pioneer in this field. (Oct 3, 2003)

Methylation status testing with Histamine Whole blood: 

• Whole Blood histamine levels are used as a marker for methylation status. Histamine, in its whole blood form, is utilized as an accurate marker for under methylation or over methylation.
• Elevated whole blood histamine levels indicate under-methylation. Review of symptoms and medical history can bolster the diagnosis. For example, most under-methylated persons exhibit seasonal allergies, perfectionism, strong wills, slenderness, OCD tendencies, high libido, depression.
• Low whole blood histamine levels indicate over-methylation. Persons who are over-methylated generally exhibit high anxiety, panic disorders, absence of seasonal allergies, presence of food/chemical sensitivities, dry eyes, low perspiration, artistic/music interests/abilities, intolerance to Prozac and other SSRI’s, etc.
• Conditions associated with under-methylation are: Anorexia, Bulimia, shopping/gambling disorders, depression, schizo-affective disorder, delusions, oppositional-defiant disorder, OCD.
• Conditions associated with over-methylation are: Anxiety/Panic disorders, anxious depression, hyperactivity, learning disabilities, low motivation, paranoid schizophrenia, hallucinations. (Oct 3, 2003) Most persons with depression, oppositional defiant disorder, OCD, bipolar disorder, or schizophrenia exhibit a genetic abnormality in methylation which appears to be central to their illness. Carl Pfeiffer, MD, PhD of Princeton, NJ was a pioneer in this field. (Oct 3, 2003)

What You Get

Test results are sent directly to you from Cometa Wellness Center. These will include Dr. Cometa’s preliminary feedback suggesting whether or not you should consider scheduling a follow-up consulting appointment with Dr. Cometa to get a full interpretation of the results.